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. Author manuscript; available in PMC: 2016 Mar 28.
Published in final edited form as: Pediatr Infect Dis J. 2015 May;34(5):520–528. doi: 10.1097/INF.0000000000000624

FIGURE 1.

FIGURE 1

A) Anti-rabies virus antibody kinetics in serum and CSF, monitored by ELISA and RFFIT. Increasing humoral immune response was elicited in both CSF and serum. RFFIT detected earlier and higher antibody titers in CSF and serum compared with ELISA. Timing of first detection of cerebral edema and stroke are illustrated. B) Anti-rabies virus class-specific antibody kinetics in serum and CSF, monitored by IFA. IgG class antibodies were detected in increasing titers in both sera and CSF, occurring in higher titers than IgM antibodies. Humoral immune responses tend to be higher in serum than in CSF.