TABLE 3.
Organism or model | AUC (95% CI) | Cutoffa | Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | Likelihood ratio (95% CI) |
---|---|---|---|---|---|
G. vaginalis | 0.90 (0.87–0.94) | 1.10E5 | 83.6 (77.2–88.8) | 84.1 (78.5–88.7) | 5.26 (3.84–7.21) |
A. vaginae | 0.92 (0.89–0.95) | 1.10E5 | 87.1 (81.2–91.8) | 90.7 (85.9–94.2) | 9.32 (6.12–14.2) |
BV | 0.87 (0.84–0.91) | 1.00E3 | 78.9 (72.1–84.8) | 92.5 (88.1–95.7) | 10.6 (6.55–17.0) |
G. vaginalis + A. vaginae | 0.96 (0.94–0.98) | 1.26E6 | 87.1 (81.2–91.6) | 93.9 (89.8–96.7) | 14.3 (8.44–24.4) |
G. vaginalis + BVAB2 | 0.93 (0.91–0.96) | 6.41E5 | 85.4 (79.2–90.3) | 90.7 (85.9–94.2) | 9.14 (5.99–13.9) |
A. vaginae + BVAB2 | 0.95 (0.93–0.98) | 1.53E5 | 92.4 (87.4–95.9) | 90.2 (85.4–93.8) | 9.42 (6.26–14.2) |
G. vaginalis + A. vaginae BVAB2 | 0.96 (0.94–0.98) | 1.17E6 | 91.2 (85.9–95.0) | 93.0 (88.7–96.0) | 13.0 (7.97–21.2) |
BICb model | 0.98 (0.97–0.99) | 0.20 | 91.8 (86.6–95.5) | 95.3 (91.6–97.7) | 19.7 (10.7–36.1) |
Cutoff is copies/reaction except for BIC, for which the cutoff is the predicted probability of the logistic regression model, where 0 = healthy and 1 = BV.
BIC, Bayesian information criterion.