TABLE 1.
Summary of sensitivities, specificities, positive predictive values, and negative predictive values of HIV rapid tests in comparison to those of EIA plus Multispot and EIA alone in Panama
| Test | Totala | Result (n)b |
Sensitivity, (% [95% CI]) | Specificity (% [95% CI]) | Predictive value (%)c |
||||
|---|---|---|---|---|---|---|---|---|---|
| TP | FP | TN | FN | Positive | Negative | ||||
| Determine | 1,503 | 465 | 0 | 1,037 | 1 | 99.8 (98.81–99.99) | 100.0 (99.64–100) | 100.0 | 99.9 |
| Uni-Gold | 1,508 | 467 | 0 | 1,039 | 1 | 99.8 (98.47–99.95) | 100.0 (99.65–100) | 100.0 | 99.8 |
| SD Bioline | 1,509 | 468 | 0 | 1,040 | 1 | 99.8 (98.82–99.99) | 100.0 (99.65–100) | 100.0 | 99.9 |
| INSTI | 1,505 | 467 | 2 | 1,035 | 1 | 99.8 (98.82–99.99) | 99.8 (98.30–99.98) | 99.6 | 99.9 |
a
Total numbers vary due to an inadequate volume of specimen or invalid results on a given rapid test.
b
TP, true positive; FP, false positive; TN, true negative; FN, false negative.
c
Predictive values are a function of HIV prevalence, so 95% CI are not included.