TABLE 2.
Summary of testing data for farmed and free-ranging elka
| Group | No. negative |
No. positive |
No. with IHC analysis of: |
No. with obex score of: |
No. tested byRT-QuIC |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| M | F | M | F | RAMALT | RLN | Obex | RLN+ Obex− | RLN− Obex+ | 0 | 1 | 2 | 3 | 4 | RAMALT | NB |
||
| KSU | RML | ||||||||||||||||
| Canada | |||||||||||||||||
| 132MM | 26 | 26 | 18 | 22 | 33 | 37 | 35 | 5 | 3 | 5 | 3 | 2 | 10 | 20 | 33 | 15 | 14 |
| 132ML | 14 | 10 | 1 | 3 | 1 | 4 | 1 | 3 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
| RMNP | |||||||||||||||||
| 132MM | NAc | NA | 4 | 4 | 4 | 4 | 0 | 0 | NA | 4 | 2b | 2b | |||||
| 132ML | NA | NA | 1 | 1 | 1 | 1 | 0 | 0 | NA | 1 | 0 | 0 | |||||
a
Ante- and postmortem RT-QuIC and IHC test results were highly correlative. Testing of RAMALT and nasal brushing (NB) samples also correlated highly with both the obex score and the PRNP genotype at position 132. All animals positive by RAMALT testing were also positive by RLN IHC analysis, while some obex-positive animals were RLN negative and vice versa. Neg, chronic wasting disease negative; Pos, chronic wasting disease positive; M, male; F, female.
b
These positive samples were from a subpopulation of the overall sample population of free-ranging elk, and represented the only two positive elk for which nasal brushings were acquired.
c
NA, not available.