TABLE 3.
Correlation | Obex | RLN | RAMALT |
NB RT-QuIC |
132MM | 132ML | Obex score of: |
||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IHC analysis | RT-QuIC | KSU | RML | 0 | 1 | 2 | 3 | 4 | |||||
Positiveb | 0.86 (<0.001)c | 0.95 (<0.001) | 0.83 (<0.001) | 0.83 (<0.001) | 0.50 (<0.001) | 0.48 (<0.001) | 0.26 (0.19) | −0.26 (0.19) | −0.86 (<0.001) | 0.24 (0.25) | 0.17 (1.00) | 0.40 (<0.001) | 0.59 (<0.001) |
RAMALT IHC analysis | 0.92 (<0.001) | 0.87 (<0.001) | 1.0 (<0.001) | 0.96 (<0.001) | 0.60 (<0.001) | 0.58 (<0.001) | 0.30 (0.04) | −0.30 (0.04) | −0.92 (<0.001) | −0.01 (1.0) | 0.21 (0.69) | 0.48 (<0.001) | 0.71 (<0.001) |
132MM | 0.32 (<0.001) | 0.23 (0.01) | 0.30 (<0.001) | 0.30 (<0.001) | 0.21 (0.02) | 0.20 (0.03) | 1.0 (<0.001) | −1.0 (<0.001) | −0.32 (0.02) | −0.01 (1.0) | 0.07 (1.0) | 0.17 (1.0) | 0.25 (0.24) |
132ML | −0.32 (<0.001) | −0.23 (0.01) | −0.30 (<0.001) | −0.30 (<0.001) | −0.21 (0.02) | −0.20 (0.03) | −1.0 (<0.001) | 1.0 (<0.001) | 0.32 (0.02) | 0.01 (1.0) | −0.07 (1.0) | −0.17 (1.0) | −0.25 (0.24) |
Including postmortem IHC results, antemortem IHC and RT-QuIC analyses of RAMALT and nasal brushings (NB), the PRNP 132 genotype, and the stage of clinical disease as assessed by obex score.
Correlation applies to tissue correlated with either an obex or an RLN sample that was positive for CWD by IHC analysis.
Shown are correlations (P values).