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. 2016 Mar 25;54(4):1065–1073. doi: 10.1128/JCM.02885-15

TABLE 4.

Performance of the multiplex immunoassay in relation to ESR and CRP resultsa

Organism(s) ESR elevatedb
ESR normal
CRP elevatedc
CRP normal
Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity
Staphylococci targeted 50/60 (83.3) [72.3–91.2] 33/45 (73.3) [59.1–84.7] 7/12 (58.3) [30.2–82.8] 157/190 (82.6) [76.7–87.5] 59/79 (74.7) [64.2–83.3] 54/68 (79.4) [68.6–87.8] 9/14 (64.3) [37.6–85.6] 152/185 (82.2) [76.1–87.2]
    S. aureus 26/34 (76.5) [60.2–88.4] d 3/6 (50) [14.7–85.3] 34/48 (70.8) [56.9–82.3] 2/5 (40) [7.3–81.8]
    S. epidermidis 20/22 (90.9) [73.1–98.4] 3/6 (50) [14.7–85.3] 21/27 (77.8) [59.4–90.5] 5/8 (62.5) [27.8–89.4]
    S. lugdunensis 6/6 (100) [60.7–100] 1/1 (100) [5–100] 7/7 (100) [65.2–100] 2/2 (100) [22.4–100]
Other staphylococci 6/7 (85.7) [47–99.3] 0/4 (0) [0–52.7] 5/9 (55.6) [24–84] 1/2 (50) [2.5,97.5]
S. agalactiae 6/8 (75) [38.8–95.6] 43/49 (87.8) [76.3–94.9] 180/192 (93.8) [89.6–96.6] 4/5 (80) [33.4–99] 64/70 (91.4) [83–96.5] 1/2 (50) [2.5–97.5] 176/189 (93.1) [88.8–96.1]
P. acnes 3/6 (50) [14.7–85.3] 45/50 (90) [79.2–96.2] 0/4 (0) [0–52.7] 166/198 (83.8) [78.2–88.5] 4/8 (50) [18.4–81.6] 59/71 (83.1) [73–90.5] 1/5 (20) [1–66.6] 167/195 (85.6) [80.2–90.1]
a

Data are no. (%) [95% confidence interval].

b

Levels of ≥30 mm/h.

c

Levels of ≥10 mg/liter.

d

—, not applicable.