TABLE 1.
The sensitivity of anti-B. henselae IgM-ELISAs performed with three antigens in comparison to IgM-IFA in the diagnosis of patients with clinically suspected cat scratch disease
| Subject category | Total no. of subjects | No. (%) of IgM-IFA-positive subjectsa | No. (%) of IgM-ELISA positive subjects |
||
|---|---|---|---|---|---|
| Ag-IIb | Ag-IVc | Ag-Vd | |||
| Patients | |||||
| Definite CSDe | 24 | 13 (54) | 18 (75) | 20 (83) | 18 (75) |
| Suspected CSD | 23 | 0 (0) | 5 (22) | 10 (43) | 6 (26) |
| Total | 47 | 13 (28) | 23 (49) | 30 (64) | 24 (51) |
| Healthy individuals | 85 | 0 | 0 | 0 | 0 |
a
IgM-IFA-positive titer, ≥1:20.
b
Ag-II, sarcosine-insoluble antigen.
c
Ag-IV, refined sarcosine-insoluble antigen.
d
Ag-V, refined sarcosine-soluble antigen.
e
CSD, cat scratch disease.