TABLE 2.
Sensitivity and specificity of Luminex xTAG GPP in comparison to real-time PCR and microbiological culturea
| Organism detected | xTAG GPP compared to real-time PCR |
xTAG GPP compared to culture |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GPP result | No. with real-time PCR result of: |
Sensitivity (% [95% CI]) | Specificity (% [95% CI]) | GPP result | No. with culture result of: |
Sensitivity (% [95% CI]) | Specificity (% [95% CI]) | |||
| Pos | Neg | Pos | Neg | |||||||
| Shigella | Pos | 86 | 6 | 95.6 (89.0–98.8) | 98.5 (96.7–99.4) | Pos | 40 | 51 | 100 (91.2–100) | 88.4 (85.0–91.2) |
| Neg | 4 | 383 | Neg | 0 | 388 | |||||
| Salmonella | Pos | 84 | 128 | 90.3 (82.4–95.5) | 66.8 (61.9–71.5) | Pos | 38 | 172 | 95.0 (83.1–99.4) | 60.8 (56.1–65.4) |
| Neg | 9 | 258 | Neg | 2 | 267 | |||||
| Campylobacter | Pos | 59 | 3 | 90.8 (81.0–96.5) | 99.3 (97.9–99.8) | Pos | 27 | 35 | 90.0 (73.5–97.9) | 92.2 (89.3–94.5) |
| Neg | 6 | 411 | Neg | 3 | 414 | |||||
| Adenovirus | Pos | 23 | 5 | 92.0 (74.0–99.0) | 98.9 (97.4–99.6) | |||||
| Neg | 2 | 449 | ||||||||
| Norovirus GI | Pos | 15 | 5 | 88.2 (63.6–98.5) | 98.9 (97.5–99.6) | |||||
| Neg | 2 | 457 | ||||||||
| Norovirus GII | Pos | 85 | 4 | 96.6 (90.4–99.3) | 99.0 (97.4–99.7) | |||||
| Neg | 3 | 387 | ||||||||
| Rotavirus | Pos | 117 | 4 | 92.9 (86.9–96.7) | 98.9 (97.1–99.7) | |||||
| Neg | 9 | 349 | ||||||||
a
GPP, gastrointestinal pathogen panel; Pos, positive; Neg, negative; 95% CI, confidence interval.