Figure 1.

Common genetic organization of four novel IncP-1ε plasmids. (A) Plasmids pSFS26 and pSFS52; (B) plasmids pSFS12 and pSFW53. The insertion sites of accessory elements in plasmids pSFS26 and pSFS52 are between parA and traC, while in pSFS12 and pSFW53 the insertion site was between trfA and klcA. Orfs are shown by arrows indicating direction of transcription. Different colors indicate replication (orange) and conjugative DNA transfer (dark blue), mating-pair formation (light blue) and central control (yellow). Hypothetical coding regions are shown in gray. The positions of the origins of vegetative (oriV) and transfer (oriT) are marked by black circles. The genes shared by the four IncP-1 plasmids are in the inner perimeter.