Table 2.
Characteristic | Unadjusted Hazard Ratio (95% CI) | P Value | Adjusted Hazard Ratio (95% CI) | P Value |
---|---|---|---|---|
Demographics | ||||
Age, y | ||||
≤25 | (ref) | <.001* | (ref) | <.001* |
26–35 | 0.61 (.38–.98) | 0.35 (.23–.52) | ||
36–45 | 0.48 (.29–.80) | 0.25 (.16–.39) | ||
>45 | 0.20 (.07–.60) | 0.11 (.03–.38) | ||
Female | 0.83 (.49–1.40) | .489 | 0.50 (.28–.90) | .021 |
Primary schooling or less | 1.05 (.81–1.36) | .726 | ||
At least 1 child | 0.90 (.68–1.19) | .464 | ||
Married | 1.07 (.75–1.53) | .72 | ||
Sexual risk factors | ||||
Multiple sex partners in last 6 mo | 0.93 (.67–1.29) | .674 | ||
Risky sexual behavior in last 6 mo | 1.16 (.90–1.50) | .245 | 1.29 (.99–1.68) | .060 |
Injection risk factors | ||||
Ever used flashblood | 1.06 (.68–1.66) | .797 | ||
Shared needles at last injection | 1.26 (.89–1.78) | .192 | ||
If shared needles, cleaned needles with bleach | 0.82 (.42–1.63) | .579 | ||
Shared other equipment at last injection | 1.04 (.69–1.57) | .843 | ||
Polysubstance use | 1.17 (.90–1.52) | .252 | ||
Mental health history | ||||
High substance dependence | 1.04 (.73–1.47) | .841 | ||
Depression in last 30 d | 0.86 (.63–1.17) | .326 | ||
Anxiety in last 30 d | 0.90 (.66–1.22) | .488 | ||
Hopkins depression score | 1.01 (.83–1.22) | .943 | ||
Hopkins overall score | 0.99 (.80–1.23) | .947 | ||
History of abuse | ||||
Any history of physical abuse | 1.06 (.72–1.56) | .759 | ||
Any history of sexual abuse | 1.84 (.82–4.46) | .14 | 2.84 (1.24–6.51) | .014 |
Criminal history | ||||
Ever arrested | 1.10 (.85–1.43) | .449 | ||
Methadone dose at initiation | ||||
<40 mg | (ref) | <.001* | (ref) | <.001* |
40–85 mg | 0.60 (.45–.81) | 0.50 (.37–.68) | ||
>85 mg | 0.47 (.34–.66) | 0.41 (.29–.59) |
Abbreviations: CI, confidence interval; ref, reference.
* Test for trend from group-linear term.