Table 1.
Subject Demographics, Clinical Characteristics and Prevalence of Hepatitis B Virus Testing
| HIV/HBV | HBV | P Value | |
|---|---|---|---|
| n = 114 (%) | n = 225 (%) | ||
| Age, mean (SD) | 45.5 (9.0) | 49.8 (12.6) | .001 |
| Female Sex | 20 (17.5) | 40 (17.8) | 1.000 |
| Ethnicity | <.00001 | ||
| Asian | 8 (7.0) | 124 (55.1) | |
| Black/African-American | 61 (53.5) | 20 (8.9) | |
| Hispanic/Latino | 23 (20.2) | 20 (8.9) | |
| Other | 6 (5.3) | 32 (14.2) | |
| White/Caucasian | 16 (14.0) | 29 (12.9) | |
| HCV coinfection | 16 (14.0) | 12 (5.3) | .129 |
| Family history of HCC | 0 (0.0) | 24 (10.7) | <.00001 |
| Tenofovir | 17 (14.9) | 102 (45.3) | <.00001 |
| Truvada | 77 (67.5) | 12 (5.3) | <.00001 |
| Lamivudine | 24 (21.1) | 11 (4.9) | <.00001 |
| Entecavir | 9 (7.9) | 75 (33.3) | <.00001 |
| Adefovir | 1 (0.9) | 21 (9.3) | .006 |
| FIB-4 Score, mean (SD) | 2.1 (1.7) | 2.9 (3.7) | .052 |
| FIB-4 Score, median | 1.7 [1.1–2.4] | 1.6 [1.0–2.8] | .643 |
| FIB-4 >3.25 | 15 (13.2) | 44 (19.6) | .188 |
| Undetectable HBV viral load, visit 1 | 34 (41.9)a | 82 (36.4) | .456 |
| Undetectable HBV viral load, visit 2 | 31 (38.3)a | 102 (45.3) | .333 |
| HBeAg Positivity, visit 1 | 19 (16.7) | 33 (14.7) | <.001 |
| HBeAg Positivity, visit 2 | 11 (9.6) | 28 (12.4) | .141 |
| Positive HCC | 2 (1.8) | 36 (16.0) | .037 |
| HCC Imaging Modality | .004 | ||
| CT scan | 16 (14.0) | 70 (31.1) | |
| MRI | 1 (0.9) | 44 (19.6) | |
| Ultrasound | 24 (21.1) | 69 (30.7) |
Abbreviations: CT, computed tomography; FIB-4, FIB-4 index score to approximate fibrosis of the liver, with score >3.25 suggestive of cirrhosis; HBeAg, hepatitis B e antigen; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C Virus; HIV, human immunodeficiency virus; MRI, magnetic resonance imaging; SD, standard deviation.
a Sample size for HIV/HBV is 81 (33 subjects did not have HBV viral load checked).