Table 1.

Key Features of the 6 Cases on Onchocerca lupi Infection

Age	Case 1	Case 2	Case 3	Case 4	Case 5	Case 6
	22 months old	10 years old	50 years old	13 years old	5 years old	10 years old
Residence	Arizona	New Mexico	Arizona	Arizona	New Mexico	Texas
Location of nodule	Cervical spine	Scalp	Forearm	Cervical spine	Cervical spine	Superior rectus muscle
Additional evaluation for parasites	Skin snipsa	Eye examb	Eye exam	Eye exam, lumbar puncture	Eye exam, lumbar puncture	None
Method of confirming the diagnosis	Histology	Histology, PCR	Histology, PCR	Histology	Histology	Histology, PCR
Histologic findings	Gravid adult	Nongravid adult	Nongravid adult	Nongravid adult	Gravid adult	Multiple nongravid adults
Management	Biopsy and ivermectinc	Nodule excision	Nodule excision, ivermectin, doxycyclined	Partial excision, ivermectin, doxycycline	Nodule excision, ivermectin, Doxycycline	Nodule excision, ivermectin, doxycycline

Abbreviation: PCR, polymerase chain reaction.

^a Skin snips are superficial skin biopsies.

^b Eye exam included a slit lamp examination of the anterior chamber of the eye, which can identify microfilariae.

^c For notes on the use of ivermectin during pregnancy or lactation and in pediatric patients please refer to http://www.cdc.gov/parasites/onchocerciasis/health_professionals/index.html#tx.

^d For notes on the use of doxycycline during pregnancy or lactation and in pediatric patients please refer to http://www.cdc.gov/parasites/onchocerciasis/health_professionals/index.html#tx.