Figure 1.

PDIMs, PGLs and chromosomal locus involved in their production. The structures are representative of those produced by M. marinum (A). The genes deleted in the M. marinum isogenic mutants analyzed in this study are highlighted with black-filled arrows (B). The roles of the gene products and the previously determined PDIM/PGL phenotype of each deletion mutant and corresponding complemented strain are outlined. The position of the enzymes missing in the mutants (*) in the biosynthetic pathway is schematically depicted (C).