Table 1.
Detection of acute coronary syndrome in observational studies
| Study | n | Population | Scanner | ACS definition | ACS rate (MI rate) | CT criterion | sens (%) | spec (%) |
|---|---|---|---|---|---|---|---|---|
| Rubinshtein et al.7 | 58 | Higher risk (incl. history of CAD) | 64-CT | Positive troponins, or >50% stenosis by invasive angiography, or positive ischaemia test | 34% | Stenosis | 100 | 92 |
| Gallagher et al.8 | 92 | Low-risk ED | 64-CT | MI, UAP | 13% | Stenosis | 86 | 92 |
| ROMICAT I9 | 368 | Low-risk ED | 64-CTa | MI (8), UAP (23) | 8.4% (2%) | Plaque | 100 | 54 |
| Stenosis | 77 | 87 | ||||||
| Hansen et al.10 | 89 | Low-risk ED | 64-DSCT | MI | 4% (4%) | Plaque | 100 | 41 |
| Stenosis | 75 | 86 | ||||||
| Dedic et al.11 | 111 | Any-risk ED (incl. low-positive troponins) | 64-DSCTa | MI (13), UAP (6) | 17% (12%) | Calcium | 89 | 41 |
| Plaque | 100 | 40 | ||||||
| Stenosis | 89 | 79 |
MI, myocardial infarction; UAP, unstable angina pectoris; sens, sensitivity; spec, specificity; DSCT, dual-source CT.
aBlinded cardiac CT exam, without affecting management.