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. Author manuscript; available in PMC: 2016 Mar 29.
Published in final edited form as: J Hand Surg Eur Vol. 2014 May 16;40(2):171–176. doi: 10.1177/1753193414535720

Table 2.

Probandwise concordance rate, odds ratio, tetrachoric correlation and heritability for DD in female Danish twins.

Zygosity Concordant
pairs (both
with DD)
Discordant pairs
(one with and
one without DD)
Concordant
pairs (both
without DD)
Probandwise
concordance
rate (95% CI)
Odds ratio
(95% CI)a
Tetrachoric
correlationb
(95% CI)
Heritability
(95% CI)
Diagnosis
Monozygotic 2 17 5609 0.27
(0.09 to 0.58)
160.3
(29.6 to 868.1)
0.77
(0.44 to 0.92)
0.81
(0.60 to 0.92)
Dizygotic 3 56 9234 0.09
(0.03 to 0.23)
36.1
(10.3 to 125.8)
0.51
(0.27 to 0.70)
Diagnosis + operation
Monozygotic 2 9 5617 0.41
(0.15 to 0.73)
561.7
(83.1 to 3,795.2)
0.87
(0.57 to 0.97)
0.89
(0.67 to 0.97)
Dizygotic 2 36 9255 0.09
(0.02 to 0.29)
67.3
(14.2 to 319.3)
0.55
(0.25 to 0.75)

CI: confidence interval; DD: Dupuytren’s disease.

a

Test-based (OR1±1.96/x2).

b

Likelihood Ratio Test for equal correlations. Diagnosis p = 0.15; diagnosis + operation p = 0.058.