Table 2.
Zygosity | Concordant pairs (both with DD) |
Discordant pairs (one with and one without DD) |
Concordant pairs (both without DD) |
Probandwise concordance rate (95% CI) |
Odds ratio (95% CI)a |
Tetrachoric correlationb (95% CI) |
Heritability (95% CI) |
---|---|---|---|---|---|---|---|
Diagnosis | |||||||
Monozygotic | 2 | 17 | 5609 | 0.27 (0.09 to 0.58) |
160.3 (29.6 to 868.1) |
0.77 (0.44 to 0.92) |
0.81 (0.60 to 0.92) |
Dizygotic | 3 | 56 | 9234 | 0.09 (0.03 to 0.23) |
36.1 (10.3 to 125.8) |
0.51 (0.27 to 0.70) |
|
Diagnosis + operation | |||||||
Monozygotic | 2 | 9 | 5617 | 0.41 (0.15 to 0.73) |
561.7 (83.1 to 3,795.2) |
0.87 (0.57 to 0.97) |
0.89 (0.67 to 0.97) |
Dizygotic | 2 | 36 | 9255 | 0.09 (0.02 to 0.29) |
67.3 (14.2 to 319.3) |
0.55 (0.25 to 0.75) |
CI: confidence interval; DD: Dupuytren’s disease.
Test-based .
Likelihood Ratio Test for equal correlations. Diagnosis p = 0.15; diagnosis + operation p = 0.058.