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. 2016 Apr;147(4):353–368. doi: 10.1085/jgp.201511510

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© 2016 Rodríguez-Banqueri et al.

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Figure 12. — Position of mutants G161N and A339D in a SteT 3-D model. Amino acid substitutions G161N and A339D were modeled in a SteT 3-D structural model (Bartoccioni et al., 2010) and represented as spheres. TMDs are represented as cylinders, and for clarity, only some of them are numbered. The G161N replacement (TMD5) introduces a new asparagine residue suggested to interact with TMD8. Similarly, the introduced aspartate in the A339D mutation (TMD9) is suggested to interact with residues in TMDs 3 and/or 4. (A) A lateral perspective of the molecule. (B) A periplasmic view after 45° rotation of A through the x axis.