Table 3.
Phenotypical characteristics of the lesions according to the four main factors previously identified as being able to favor the infiltration of Mtb-infected lesions with PMNs.
| Max-Ibac (BLTOL) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 16 | 32 | 64 | |||||||
| Breathing Amplitude (BAM) | 0.1 | C | C | C | C | C | C | 1 | Anti-Th17 |
| 0.2 | A | B | B | B | C | C | |||
| 0.3 | A | A | B | B | B | B | |||
| 0.1 | B | B | D | D | D | D | 10 | ||
| 0.2 | A | B | B | B | D | D | |||
| 0.3 | A | A | B | B | B | D | |||
| − | + | − | + | − | + | ||||
| Encapsulation | |||||||||
These are the tolerability of infected macrophages to the bacillary load (BLTOL); the capacity to modulate the Th17 response; the breathing amplitude (BAM); and the encapsulation of Mtb-infected lesions. These results are obtained after running the program until day 46 post-challenge. Figure 10 shows the phenotype. Type A.- In dark blue, proliferative in progression, with low quantities of Dbac and a high proportion of Kbac. Type C.- In red, exudative, based on a large necrotic center surrounded by an active ring of alveoli filled with PMNs and the massive presence of Dbac. Type D.- In orange, exudative controlled, with smaller lesions than in type C surrounded by a ring of aAMs. Type B.- In sky blue, proliferative controlled, as there is a very low quantity of Dbac and a very high proportion of Kbac.