Figure 5.

Neutrophils recovered from the bladders of infected HDAC6^−/− contain higher numbers of viable bacteria. (A) Representative flow plots of bladder neutrophils recovered from the bladders of WT and HDAC6^−/− following a 90-min infection with UPEC. Neutrophils were identified by gating on CD45⁺ populations and then on CD11b⁺Ly6G⁺ cells; (B) Numbers of neutrophils sorted from WT and HDAC6^−/− bladders; (C) Numbers of viable UPEC recovered from neutrophils after sorting from WT and HDAC6^−/− bladders. Data in (B) and (C) are expressed as the means ± SEM of 5 independent experiments. p values were determined using unpaired Student’s t tests.