Figure 2.

Transmission Electron Microscopy (TEM) of heart samples from control and DA-treated rats. (A) Cardiomyocyte from of a control specimen showing the typical arrangement of myofibrils and mitochondria (M); (B) Ultrastructure of rat cardiac muscle from a DA-treated rat. A moderate lysis of myofibrils (arrows) and degeneration of mitochondria (M) can be observed; (C) Cardiomyocyte from a control specimen showing mitochondria (M) with their usual shape and electron density; (D) Cardiomyocyte from DA treated rat showing degenerated mitochondria (M). These organelles had lost their habitual rounded shape, they were less electron dense than mitochondria of control animals and displayed cristolysis.