Table 1.
Name | Type/Region of Polymer | Function | Mode of Interaction * | PDB Code | Ref. |
---|---|---|---|---|---|
Ribosome A site | 23S RNA; helix 38 and others | Translation | H,V | 4V6F | [13] |
Ribosome P site | L5 protein and others | Translation | H,V | 4V51 | [10] |
Ribosome E site | 23S RNA; L1 stalk and others | Translation | S | 4V4I | [11] |
RNase P | RNA: J11/12–J12/11 | tRNA modification: 5′ end maturation | S | 3Q1Q | [14] |
T-box riboswitch | RNA: Stem I distal region | Amino acid surveillance: tRNA binding, recognition of aminoacylation, and genetic switching | S | 4LCK | [15] |
LeuRS | protein | tRNA aminoacylation | H, V | 2V0G | [16] |
ValRS | protein | tRNA aminoacylation | H, V | 1GAX | [17] |
GatDE | protein | Aminoacyl-tRNA transamidation | unknown | 2D6F | [18] |
GatCAB | protein | Aminoacyl-tRNA transamidation | H, V | 3AL0 | [19] |
RNase Z | protein | tRNA modification: 3′ end maturation | H, V | 4GCW | [20] |
DusC | protein | tRNA modification: reduction of D-loop U16/U20 to dihydrouridine | H, V | 4YCP | [21] |
TruB | protein | tRNA modification: pseudouridylation of T-loop U55 to Ψ | T-loop extraction | 1K8W | [22] |
ArcTgt | protein | tRNA modification: transglycosylation of D-loop G15 to PreQ0. | D-loop extraction | 1J2B | [23] |
CCA-adding enzyme | protein: tail domain | tRNA maturation; addition of 3′ CCA trinucleotide | H,V | 1SZ1 | [24] |
CC-adding enzyme | protein: tail domain | tRNA maturation; addition of 3′ C nucleotides | H,V | 3WFR | [25] |
A-adding enzyme | protein | tRNA maturation; addition of 3′ A nucleotide | H,V | 4X0B | [26] |
* H: Hydrogen bonds; S: Stacking interaction; V: van der Waals interaction.