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. 2016 Mar 2;31(4):535–541. doi: 10.3346/jkms.2016.31.4.535

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© 2016 The Korean Academy of Medical Sciences.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1 — Effects of Ang II on the localization of p130Cas in podocytes. p130Cas stainings are located in the cytoplasm of cultured podocytes diffusely, whereas, F-actin fibers are distributed in peripheral cytoplasm and run over nucleus, apart from p130Cas. (A) Ang II reduces and re-localizes the immunofluorescent intensities of p130Cas in internal cytoplasm and peri- and intra-nuclear areas of podocytes with concentrations. Such changes by Ang II are associated with disrupted F-actin fibers. (B) Ang II (10^-6 M) also decreases and concentrates the immunofluorescent intensities of FAK (arrow) in internal cytoplasm and peri-nuclear areas of podocytes, which become to be separated partially from p130Cas (arrow head). Magnification, × 1,000.