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. 2016 Mar 10;31(4):553–560. doi: 10.3346/jkms.2016.31.4.553

Table 3. Medications of the COPD subjects according to the GOLD group A to D at inclusion.

Medication* No. (%) of patients P value
GOLD A GOLD B GOLD C GOLD D
LAMA 68 (48.2) 204 (40.6) 29 (41.4) 227 (34.2) < 0.001
LABA 18 (12.8) 47 (9.4) 6 (8.6) 33 (4.8) < 0.001
ICA + LABA 28 (19.9) 122 (24.3) 21 (30.0) 189 (28.5) < 0.001
ICA + LABA + LAMA 18 (12.8) 74 (14.7) 18 (25.7) 153 (23.0) < 0.001
PDE4 Inhibitor 2 (1.4) 5 (1.0) 2 (2.9) 35 (5.3) < 0.001
Xanthine oxidase inhibitor (Theophylline) 22 (15.6) 107 (21.3) 10 (14.3) 141 (21.3) < 0.001
Oral beta 2 agonist 3 (2.1) 17 (3.4) 2 (2.9) 38 (5.7) < 0.001

*Multiple responses for medication. COPD, chronic obstructive pulmonary disease; GOLD, global initiative for chronic obstructive lung disease; LAMA, long acting muscarinic antagonist; LABA, long acting beta-2 agonist; ICA, inhaled corticosteroid; PDE4 inhibitor, phosphodiesterase 4 inhibitor.