Table 1. Expression patterns of putative virulence factors gained at the Leishmaniinae node.
| OG | Gene IDs | Annotation | Upregulated in |
||
|---|---|---|---|---|---|
| L. seymouri | L. mexicana | L. majorFriedlin | |||
| 06971 | LmjF.19.0840, LmjF.19.0844, LmjF.19.0848, LbrM2903_19_0920, LbrM.19.1140, LdBPK_190840.1, LinJ.19.0840, LmxM.19.0870, LtaP19.0810 | ATG8/AUT7/APG8/PAZ2 (ATG8A.1) | 35 °C | META | VIRULENT |
| 09307 | LdBPK_051210.1, LinJ.05.1210, LmjF.05.1215, LmxM.05.1215, LbrM2903_05_1260, LbrM.05.1210, LtaP05.1300 | surface antigen-like protein | 35 °C | PRO and META | VIRULENT |
| 09635 | LbrM2903_27_2010, LbrM.27.1900, LdBPK_271680.1, LinJ.27.1680, LmjF.27.1780, LmxM.27.1780, LtaP27.1830 | casein kinase I-like protein | no significant changes | META and AMA | VIRULENT |
| 10354 | LdBPK_312140.1, LinJ.31.2140, LmjF.31.2090, LmxM.30.2090, LtaP31.2520 | protein with unknown function | 35 °C | AMA | no significant changes |
Only Leishmania spp. gene IDs are shown. Leishmania life cycle stages are abbreviated as follows: PRO, procyclics; META, metacyclics; AMA, amastigotes.