TABLE 2 .
Growth on or metabolism of three steroids by nine predicted steroid degradersa
| Phylum | Strain | Steroid substrate |
||
|---|---|---|---|---|
| Cholesterol | Cholate | Testosterone | ||
| Proteobacteria | Pseudomonas resinovorans NRBC106553 | – | – | G, R |
| Cupriavidus necator ATCC 17699 | – | – | G, R | |
| Sphingomonas wittichii RW1 | – | – | G, R | |
| Shewanella pealeana ATCC 700345 | – | R, a | T, a | |
| Actinobacteria | Thermomonospora curvata ATCC 19995 | – | G, R | T |
| Actinoplanes missouriensis 431 | G, R, t | – | T | |
| Salinispora arenicola CNS-205 | R, a, c/t | – | T | |
| Amycolicicoccus subflavus DQS3-9A1T | R, a, c | – | – | |
| Amycolatopsis sp. strain ATCC 39116 | G, R | R, a | G, R, c | |
a
Symbols: −, no growth or metabolism; G, growth on steroid as sole organic substrate; T, transformation of steroid to metabolites; R, complete removal of steroid with no detectable metabolite accumulation; t, tyloxapol required; c, methyl-β-cyclodextrin required; c/t, either tyloxapol or cyclodextrin required; a, metabolism in the presence of an additional organic substrate.