Table 7.
Effect of ethanol extract of S. jambos and indomethacin on histamine-induced oedema paw volume in wistar rats
| Treatment | Dose | Right hind paw volume (% Inhibition) | ||||
|---|---|---|---|---|---|---|
| (mg/kg) | 1 h | 2 h | 3 h | 4 h | 5 h | |
| Vehicle | 10 (ml/kg) | 1.10 ± 0.15 | 1.25 ± 0.19 | 1.34 ± 0.18 | 1.40 ± 0.22 | 1.52 ± 0.21 |
| Indomethacin | 10 | 0.56 ± 0.14 (49.09)* | 0.57 ± 0.16 (54.40)* | 0.58 ± 0.15 (56.72)* | 0.53 ± 0.19 (62.14)** | 0.52 ± 0.13 (65.79)** |
| S. jambos | 200 | 0.76 ± 0.11 (30.91) | 0.80 ± 0.17 (36.00)** | 0.86 ± 0.23 (35.82)* | 0.84 ± 0.15 (40.00)** | 0.82 ± 0.18 (46.05)** |
| S. jambos | 400 | 0.67 ± 0.13 (39.09) | 0.69 ± 0.14 (44.80)* | 0.72 ± 0.16 (46.27)* | 0.74 ± 0.14 (47.14)* | 0.70 ± 0.19 (53.95)** |
Each value is presented as the mean ± SEM (n = 5)
* P < 0.05 compared with control group (Dunnett’s test)
** P < 0.01 compared with control group (Dunnett’s test)