TABLE 1.
Statistical comparison of numbers of broadly neutralizing plasma samples (based on the indicated criteria) between HIV-1-infected humans and SHIVSF162P3N-infected macaques
| Criterion | Neutralization | No. of plasma samples |
||
|---|---|---|---|---|
| Humans 1–3 yr p.i. | Macaques 1–2 yr p.i. | Total no. | ||
| Neutralizing ≥5 out of 10 tested HIV-1 strains with an ID50 of >100a | Broad | 2 | 5 | 7 |
| Not broad | 40 | 8 | 48 | |
| Total no. | 42 | 13 | 55 | |
| Neutralizing ≥5 out of 10 tested HIV-1 strainsb | Broad | 4 | 5 | 9 |
| Not broad | 38 | 8 | 46 | |
| Total no. | 42 | 13 | 55 | |
a
Fisher's exact test, P = 0.006; chi-square test, P = 0.001.
b
Fisher's exact test, P = 0.026; chi-square test, P = 0.014.