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MCMV ΔM45::MC159 does not replicate in endothelial cells, but ΔM36::MC159 replicates in macrophages. SVEC4-10 cells (A) or RAW 264.7 macrophages (B) were infected at an MOI of 0.5 TCID50/cell with the viruses indicated. Supernatants were collected at the indicated days postinfection, and virus titers were determined. Means ± SEM for experiments done in triplicate are shown. DL, detection limit.
