Fig. 6.
Nrf2 deficiency on American ginseng crude extract- and subfraction-mediated suppression of iNOS expression in macrophages. Bone-derived macrophages of WT and Nrf2−/− mice were treated with LPS, (A) American ginseng crude extracts (Am. G), and (B) panaxynol in DMEM supplemented with 2% FBS as indicated for 6 h. Left panel: qPCR analysis. n=6, *p<0.05 vs. control (−) in each group. Right panel: Representative immunoblotting of 3 separate experiments.