Table 1.

Baseline characteristics (general)

	Fluvoxamine N = 17	Placebo N = 16	P-value
Male/Female	4/13	6/10	0.38
PBC/PSC	12/5	10/6	0.57
Age (median)	51	54	0.38
Pruritus (yes/no)	9/8	8/8	0.87
UDCA dose (median, mg/day)	750	900	0.14
Previous depressive disorder (yes/no)	(0/17)	(1/15)	0.30
Weight (median, kg)	67	71	0.95
Length (median, cm)	173	171	0.67
Body Mass Index (median)	24.2	24.6	0.61
Haemoglobin (mmol/l, median)	8.3	8.8	0.21
Bilirubin (μmol/l, median)	13	11.5	0.83
Alkaline Phosphatase (U/l, median)	137	192	0.36
ALT (U/l, median)	42	43	0.55
Albumin (U/l, median)	42	41.5	0.81

Laboratory reference values: haemoglobin 7.5–9.5 mmol/l, bilirubin 0–16 μmol/l, alkaline phosphatase 0–119 U/l, ALT 0–30 U/l, albumin 35–50 g/l.