FIG 1.

Monocyte subset frequencies in HTLV-1-infected and uninfected individuals. (A) Gating strategy for monocytes. PBMCs from uninfected and HTLV-1-infected individuals were stained with anti-CD3, anti-CD14, and anti-CD16 antibodies. (a) Side scatter (SSC-A) and forward scatter (FSC-A) define two distinct clusters of monocytes and lymphocytes. (b) The monocytes were gated according to the levels of CD14 and CD16 expression in the quadrants that included classical monocytes (top left), intermediate monocytes (top right), and nonclassical monocytes (bottom right). (c) The boxes indicate the populations collected during sorting. (B) Frequency of monocyte subsets in HTLV-1-infected and uninfected individuals. Open symbols, HTLV-1-infected patients with no symptoms of HAM/TSP. (C) Frequency of monocyte subsets in HTLV-1-infected individuals with (closed symbols) or without (open symbols) HAM/TSP. The statistical analysis was performed using the Wilcoxon rank sum test. ns, no statistically significant difference.