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In vivo infection by luciferase-expressing MuHV-4 strains. Female mice were infected intranasally (1 × 104 PFU) with MuHV-4 WT Luc (top row) or ORF63 STOP Luc (bottom rpw) strains under general anesthesia. The mice were then injected with luciferin and imaged at the indicated time points. Images show a representative mouse (from a group of 5 mice) at days 3, 5, 7, 10, 12, 14, 17, and 19 p.i. The scale bar shows the color scheme for signal intensity.
