FIG 2.

RSV infection upregulated levels of MMP-12. MMP-12 gene and protein expression and the concentration of MMP-12 in BALF were determined by qPCR, Western blotting, and ELISA, respectively, at early and later stages of RSV infection. (A) MMP-12 gene expression; (B) MMP-12 protein expression; (C) level of MMP-12 in BALF. Results are representative of two independent experiments, with a total of 5 to 7 mice/group, and all data are presented as means ± SEM. P < 0.05 (*), P < 0.01 (**), and P < 0.001 (***) compared to mock treatment.