TABLE 1.
Immunophenotyping of lymphocytes in the spleen of naive WT and Ifi27l2a−/− micea
| Cell type | Cell type subset | WT |
Ifi27l2a−/− |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Absolute no. |
Percent |
Absolute no. |
Percent |
||||||
| Avg | ±SD | Avg | ±SD | Avg | ±SD | Avg | ±SD | ||
| CD4+ | 2.84E + 06 | 4.74E + 05 | 14.20 | 1.78 | 2.95E + 06 | 2.72E + 05 | 14.13 | 1.08 | |
| CD44high CD62llow | 3.05E + 05 | 2.26E + 04 | 10.88 | 1.08 | 3.52E + 05 | 8.57E + 04 | 11.93 | 2.85 | |
| CD44low CD62lhigh | 2.10E + 06 | 4.22E + 05 | 73.60 | 2.68 | 2.14E + 06 | 2.56E + 05 | 72.39 | 5.09 | |
| CD8+ | 2.01E + 06 | 3.23E + 05 | 10.04 | 1.06 | 2.05E + 06 | 2.67E + 05 | 9.79 | 0.62 | |
| CD44high CD62llow | 3.41E + 04 | 6.47E + 03 | 1.75 | 0.47 | 4.69E + 04 | 2.19E + 04 | 2.31 | 1.13 | |
| CD44low CD62lhigh | 1.93E + 06 | 3.19E + 05 | 96.20 | 0.94 | 1.95E + 06 | 2.79E + 05 | 94.93 | 2.77 | |
| CD19+ | 1.39E + 07 | 2.43E + 06 | 69.26 | 2.65 | 1.43E + 07 | 2.01E + 06 | 67.86 | 2.63 | |
| IgMhigh | 1.36E + 07 | 2.34E + 06 | 98.14 | 0.31 | 1.40E + 07 | 1.91E + 06 | 98.02 | 0.29 | |
| NK | 4.80E + 05* | 8.13E + 04 | 2.41* | 0.30 | 7.31E + 05* | 1.13E + 05 | 3.47* | 0.21 | |
a
Data represent means (Avg) ± standard deviations (SD) for cells from WT and Ifi27l2a−/− mice (n = 5 mice each; *, P < 0.05). The percentages of the indicated populations were calculated as proportions of the total parent populations.