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(a) Structure of paclitaxel–polylactide (Ptx-PLA) and formation of KLWVLPK peptide-functionalized lipid–polymer hybrid nanoparticles composed of a Ptx-PLA core and a PEGylated lipidic shell. (b) Human aortic smooth muscle cell (haSMC) cytotoxicity study showing the targeted drug release from KLWVLPK peptide-functionalized hybrid nanoparticles. Adapted with permissions from ref (79).
