Fig. 6.

Comparison of airborne transmission of experimental passaged A/H5N1 and 2009 pandemic A/H1N1 viruses in individual ferrets. A throat-swab sample from ferret F2 at 7 days postexposure (dpe) (Fig. 5D) was used for the transmission experiments shown in (A) and (B), and a virus isolate obtained from a nose swab collected from ferret F5 at 7 dpi (Fig. 6A) was used for the experiments in (C) and (D). For comparison, published data on transmission of 2009 pandemic A/H1N1 virus between ferrets is shown in (E) to (H) (27). Data for individual transmission experiments is shown in each panel, with virus shedding in inoculated and airborne virus–exposed animals shown as lines and bars, respectively. For the transmission experiments with airborne-transmissible A/H5N1 (A to D), nose or throat swabs were not collected at 2 dpi and 2 dpe. White circles and bars represent shedding from the nose; black circles and bars represent shedding from the throat. The asterisk indicates the inoculated animal that died 6 days after intranasal inoculation.