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The relationship between microRNA and TGF-β1/SMAD in hepatic fibrosis. In hepatic fibrosis, miR-146a, miR-454 and miR200a negatively correlate with SMAD4 and SMAD3, respectively. In addition, miR-199a, and miR-33a and miR-21 are positively associated with SMAD3 and SMAD7, respectively.
