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. 2014 Jun 30;35(48):3442–3451. doi: 10.1093/eurheartj/ehu254

Table 4.

Unadjusted and adjusted β-coefficients for parameters of cardiovascular structure and function significantly different at univariable analyses by estimated glomerular filtration rate and urinary albumin-to-creatinine ratio combined categories

Normal UACR/preserved eGFR High UACR /preserved eGFR Normal UACR/low eGFR High UACR/low eGFR
LVEDV (mL) Reference Unadjusted β-coefficient 22.9** 0.5 8.9
Adjusted β-coefficient 13.9* 3.4 1.0
LVESV (mL) Reference Unadjusted β-coefficient 11.8** −1.3 2.6
Adjusted β-coefficient 6.3 0.3 −2.7
SWT (cm) Reference Unadjusted β-coefficient 0.07 0.13** 0.09**
Adjusted β-coefficient 0.06 0.13** 0.08*
PWT (cm) Reference Unadjusted β-coefficient 0.05 0.08** 0.09**
Adjusted β-coefficient 0.03 0.08* 0.06*
LVM (g) Reference Unadjusted β-coefficient 27** 21** 25**
Adjusted β-coefficient 16 22** 15
LVMi (g/m2.7) Reference Unadjusted β-coefficient 4.2** 5.8** 5.3**
Adjusted β-coefficient 3.6 4.5* 4.3
RWT (cm) Reference Unadjusted β-coefficient 0.000 0.041** 0.035*
Adjusted β-coefficient −0.001 0.036* 0.033
Cardiac output (L/min) Reference Unadjusted β-coefficient 914** 105 351
Adjusted β-coefficient 712** 322 276
MWFS (%) Reference Unadjusted β-coefficient −0.25 −1.20** −0.82*
Adjusted β-coefficient −0.19 −1.22** −0.98*
NT-proBNP (pg/mL) Reference Unadjusted β-coefficient 148 341 840**
Adjusted β-coefficient 48 287 741**

LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; SWT, septal wall thickness; PWT, posterior wall thickness; LVM, left ventricular mass; LVMi, left ventricular mass indexed to height2.7; RWT, relative wall thickness; MWFS, midwall fractional shortening.

Adjusted for age, sex, PP, previous admission for HF, history of diabetes, anaemia.

*P < 0.05 for comparison vs. reference (both eGFR and UACR normal).

**P < 0.01 for comparison vs. reference (both eGFR and UACR normal).