Table 2.

Variables associated with all-cause hospitalization at P<0.1 in each stratum

Stratum	Variables associated with all-cause hospitalization	Hazard ratio* (95% CI)	P-value
All (n=403)	Low number of medications (<10) Medium number of medications (10-16) High number of medications (>16) Renal co-morbidity Prescription of ACEI/ARB	0.46 (0.24 to 0.86) Reference variable 1.06 (.7 to 1.61) 1.49 (0.99 to 2.26) 0.57 (.39 to .84)	0.016 – 0.799 0.057 0.004
High illness severity (n=219)	Psychiatric co-morbidity	0.51 (0.25 to 1.06)	0.071
Low illness severity (n=184)	Psychiatric co-morbidity Prescription of ACEI/ARB	3.21 (1.3 to 7.9) 0.31 (0.14 to 0.67)	0.012 0.003
Males (n=181)	Severe dyspnoea Anaemia co-morbidity Thyroid co-morbidity Living alone Neurological co-morbidity Prescription of ACEI/ARB	1.9 (1.07 to 3.4) 2.57 (1.31 to 5.06) 2.39 (1.17 to 4.87) 0.34 (.15 to 0.79) 0.27 (0.06 to 1.15) 0.47 (0.26 to 0.87)	0.03 0.006 0.016 0.012 0.076 0.015
Females (n=222)	Prescription of beta-blocker Renal system co-morbidity Pulmonary co-morbidity	2.12 (1.0 to 3.06) 1.9 (1.08 to 3.37) 1.82 (1.08 to 3.06	0.051 0.027 0.025
<75 years age (n=78)	Prescription of beta-blocker Pulmonary co-morbidity Obesity	4.14 (0.94 to 18.21) 3.43 (1.12 to 10.5) 2.69 (1.0 to 7.19)	0.06 0.031 0.048
75–84 years age (n=110)	–	Model not significant
>84 years age (n=215)	No anxiety Low number of medications (<10) Medium number of medications (10-16) High number of medications (>16) Arrhythmia co-morbidity Primary HF diagnosis	0.55 (0.3 to 1.01) 0.4 (0.18 to 0.91) Reference variable 1.46 (0.78 to 2.75) 0.6 (0.36 to 1.0) 1.68 (0.98 to 2.87)	0.054 0.028 – 0.236 0.051 0.06

^*Increase in odds ratio associated with 1 unit increase in predictor