Table 3.
Stratum | Variables associated with cardiac related hospitalization | Hazard ratio* (95% CI) | P-value |
---|---|---|---|
All (n=403) | Low number of medications (<10) Medium number of medications (10-16) High number of medications (>16) Primary HF diagnosis Prescription of ACEI/ARB |
0.32 (0.14 to 0.76) Reference variable 1.1 (0.66 to 1.84) 1.48 (0.93 to 2.36) 0.59 (0.37 to 0.94) |
0.009 – 0.718 0.096 0.027 |
High illness severity (n=219) |
Psychiatric co-morbidity Prescription of diuretic Diabetes co-morbidity |
0.26 (0.1 to 0.82) 0.48 (0.26 to 0.89) 0.51 (0.29 to 0.89) |
0.022 0.02 0.018 |
Low illness severity (n=184) |
Prescription of ACEI/ARB Psychiatric co-morbidity |
0.42 (0.15 to 1.16) 4.27 (1.36 to 13.41) |
0.095 0.013 |
Males (n=181) | Prescription of ACEI/ARB | 0.62 (0.39 to 0.98) | 0.043 |
Females (n=222) | Low number of medications (<10) Medium number of medications (10-16) High number of medications (>16) New HF diagnosis |
0.26 (0.06 to 1.12) Reference variable 1.58 (0.78 to 3.2) 2.2 (0.91 to 5.3) |
0.071 – 0.209 0.08 |
<75 years age (n=78) |
Obesity | 4.29 (1.25 to 14.67) | 0.02 |
75–84 years age (n= 110) | None | Model not significant | |
>84 years age (n=215) |
Low number of medications (<10) Medium number of medications (10-16) High number of medications (>16) Primary HF diagnosis |
0.36 (0.1 to 1.0) Reference variable 1.77 (0.85 to 3.67) 2.4 (1.12 to 4.8) |
0.056 – 0.126 0.013 |
Increase in odds ratio associated with 1 unit increase in predictor