Table 3. Terms used for the description of the algorithm.

Term	Explanation
Lab value curve	The normalized laboratory values of one medication episode.
Pre-phase	The time period before the first application of the drug.
Mid-phase	The time period from the first application of the drug until the last application of the drug.
Post-phase	The time period after the last application the drug.
Fitted curve	An artificially generated signal curve that has been fitted to the lab value curve (i.e., parameters like slope and intercept of the fitted curve have been optimized to match the lab value curve by means of the Levenberg–Marquardt algorithm Moré, 1978).
Low-pass filtered data	The lab value curve after application of a one-dimensional Gaussian low-pass filter (Haddad & Akansu, 1991) (σ = 1.5).
Removed outliers	The lab value curve after replacement of the two most extremely deviating values by the median.