Table 1.
Experimental studies using cell therapy in silicosis.
Model | Cell type | Route | Number of cells | Follow-up | Reference |
---|---|---|---|---|---|
C57BL/6 | BMDC | i.t. | 2 × 106 | 30 and 60 days | [96] |
C57BL/6 | BMMC | i.v. | 2 × 106 | 15 days | [97] |
Nude mice | HUES-3 | i.t. | 2.5 × 106 | 15 days | [98] |
Sprague-Dawley | BMSC | i.t. | 3 × 106 | 14 days | [99] |
C57BL/6 | BMDC | i.t. | 2 doses of 2 × 106 | 60 days | [36] |
C57BL/6 | BMSC | i.v. | 2 × 105 | 15 and 30 days | [100] |
C57BL/6 | BMMC | i.v. | 1 × 106 | 70 days | [16] |
BMDC: bone marrow-derived cells; BMMC: bone marrow mononuclear cells; BMSC: bone marrow-mesenchymal stromal cells; HUES: human embryonic stem cells; i.t.: intratracheal; i.v.: intravenous.