Table 2. – Dermatomyositis and male fertility.
| Author | Year | Study Population | Results | Conclusion |
|---|---|---|---|---|
| Moraes et al. (19) | 2008 | 5 post-pubertal males with DM and 5 healthy controls | 100% teratozoospermia / Azoospermia during CYC treatment | No significant difference between patients and normal controls regarding hormonal levels or sperm analysis |
| Moraes et al. (20) | 2010 | 10 post-pubertal males with DM and 10 healthy controls | Low concentration, low sperm abnormalities, low motile count, reduced testicular volumes in DM patients | DM may affect testicular function and sex hormones levels / Disease activity and CYC may induce gonadal dysfunction |
Note: DM = dermatomyositis; CYC = cyclophosphamide.