TABLE 2.

mtDNA CN/Cell, mtDNA Deletions, and p53 Gene Copy Ratios in TD and AU Trios

Outcome	Children			Mothers of			Fathers of
CN	TD	AU	P	TD	AU	P	TD	AU	P
mtDNA (±SEM)	184 (±7)	212 (±8)	.012	205 (±9)	207 (±9)	.875	195 (±9)	180 (±8)	.237
n	46	66		36	48		36	47
Deletions in mtDNA (±SEM)	1.00 (±0.02)	0.98 (±0.02)	.458	0.83 (±0.01)	0.87 (±0.01)	.206	0.86 (±0.02)	0.88 (±0.02)	.520
n	46	66		35	46		37	48
p53 gene copy ratio (±SEM)	1.00 (±0.02)	1.05 (±0.01)	.055	1.09 (±0.04)	0.93 (±0.04)	.009	1.07 (±0.02)	0.98 (±0.02)	.055
n	44	60		36	47		37	46

mtDNA deletions and p53 gene copy ratio values were normalized to TD children. Statistical analysis was performed with the 2-tailed Student’s t test.