TABLE 2.
Primary Outcome: Gross Motor Development Assessed According to the PDMS-2 at 9 Months
| Subscale | Mean (95% CI) | Pa | Effect Size d | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Timing | Duration | ||||||||||
| PP (n =288) | PI (n =305) | IP (n =298) | II (n =305) | IP Versus PI | IP versus PP | PI Versus PP | II Versus IP | II Versus PI | II Versus PP | ||
| Reflexes | 14.4 (14.3–14.6) | 14.6 (14.5–14.7) | 14.4 (14.3–14.6) | 14.7 (14.5–14.8) | .03 | 0.16 | 0.00 | 0.16 | 0.18b | 0.03 | 0.19b |
| Stationary | 33.5 (33.4–33.7) | 34.0 (33.8–34.1) | 33.4 (33.3–33.6) | 34.0 (33.8–34.1) | <.001 | 0.35b | 0.08 | 0.28b | 0.37b | 0.01 | 0.29b |
| Locomotion | 39.5 (38.7–40.2) | 41.4 (40.7–42.2) | 39.5 (38.8–40.3) | 41.3 (40.5–42.0) | <.001 | 0.30b | 0.01 | 0.30b | 0.27b | 0.03 | 0.28b |
| Overall gross motor | 87.5 (86.5–88.4) | 90.0 (89.0–90.9) | 87.4 (86.4–88.3) | 89.9 (89.0–90.8) | <.001 | 0.31b | 0.01 | 0.30b | 0.30b | 0.01 | 0.29b |
CI, confidence interval; II, iron in pregnancy/iron in infancy; IP, iron in pregnancy/placebo in infancy; PI, placebo in pregnancy/iron in infancy; PP, placebo in pregnancy/placebo in infancy. Subscale n values vary slightly due to missing data.
a
Analysis of covariance model covarying age at testing. Pairwise comparisons expressed as effect size d (difference between means divided by pooled SD).
b
Significant difference between groups, P < .05.