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The average optical density values of the immunohistochemical staining for HIF-1α expression in the control and experimental groups at different time-points.
| Group | Day 1 | Day 3 | Day 7 | Day 14 | F | P-value |
|---|---|---|---|---|---|---|
| Control | 57.87±4.36 | 75.27±3.36 | 95.41±4.81 | 138.0±4.30 | 328.88 | <0.001 |
| Experimental | 54.39±2.18 | 68.04±3.25 | 83.54±3.77 | 88.21±4.51 | 96.195 | <0.001 |
| t | 1.577 | 3.456 | 4.338 | 17.881 | ||
| P-value | 0.154 | 0.009 | 0.002 | <0.001 |
