Figure 1. Analysis of EMT-related protein expression changes in locally advanced invasive prostate cancer.

The expression profiles of eleven candidate EMT-related proteins were analysed in extraprostatic and intraprostatic regions of 27 cases of locally advanced invasive prostate cancer in radical prostatectomy specimens. Significantly increased cytoplasmic α-smooth muscle actin, increased cytoplasmic E-cadherin, decreased membranous E-cadherin, and decreased membranous Snail expression (*adjusted-p < 0.05 for each) was observed in extraprostatic foci of prostate cancer compared with intraprostatic tumour.