Figure 2. Ectopic expression of miR-630 suppresses Transwell migration, Matrigel invasion and colony formation in breast cancer cells in vitro .
A. Transwell migration assay measuring breast cancer cell migration in 231-LUC (top) and BT-549 (bottom) transiently transfected with miR-NC or mature miR-630 mimics, respectively. B. Matrigel invasion assay measuring breast cancer cell invasion in 231-LUC (top) and BT-549 (bottom) transfected with miR-NC or mature miR-630 mimics. Data represent mean ± SD of nine randomly selected areas from three independent experiments. C, D. Analysis of colony formation in 231-LUC cells (C) and BT-549 cells (D) transiently transfected with miR-NC or mature miR-630 mimics, respectively. **P < 0.01; ***P < 0.001. All experiments were repeated independent three times.