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. 2015 Nov 29;7(2):1500–1515. doi: 10.18632/oncotarget.6430

Figure 7. In vivo effects of dl922-947 on tumor macrophage density and polarization.

Figure 7

A. Real-Time PCR analysis of CCL2 mRNA levels in tumors excised at day 8 (5/group) treated as described in Figure 6A. Student's t test: **p<0.01. B. Representative histological analysis of F4/80 expression in tumor samples excised at day 8 treated as described in Figure 6A. Red arrows indicate illustrative F4/80-positive cells (macrophages). C. Real-Time PCR analysis of mRNA levels of the M2 (Ym1, Arg1) and M1 (Nos2) markers in tumors excised at day 8 (5/group) treated as described in Figure 6A. Student's t test: *p<0.05. D. Real-Time PCR analysis of Ifng mRNA levels in tumors excised at day 8 (5/group) treated as described in Figure 6A. Student's t test: *p<0.05.