Table 7. Rev-GFP and MTT IC50 values for unmodified and biotinylated SINE compounds.
Compound | Rev GFP IC50 (nM) | MTT IC50 (nM) |
---|---|---|
KPT-276 | 53 | 18 |
KPT-9058 (biotinylated KPT-276) | 961 | 110 |
KPT-8602 | 42 | 19 |
KPT-9511 (biotinylated KPT-8602) | 230 | 280 |