Table 4. Precision and accuracy of the CKD-EPI and Schwartz equations according to age and mGFR in children and adolescents.
mGFR Category and Performance Index | All Participants <18 y | Children (2–12 y) | Adolescents (13–17 y) | |||
---|---|---|---|---|---|---|
CKD-EPI | Schwartz | CKD-EPI | Schwartz | CKD-EPI | Schwartz | |
All mGFR categories | ||||||
IQR (95% CI) | 0.33 (0.31; 0.34) | 0.23 (0.21; 0.24) | 0.39 (0.37; 0.42) | 0.22 (0.20; 0.23) | 0.35 (0.31; 0.41) | 0.21 (0.22; 0.27) |
P10 (95% CI) | 8.4 (6.0; 10.0) | 46.7 (44.0; 49.6) | 2.8 (1.6; 4.0) | 49.1 (45.5; 52.6) | 18.1 (14.3; 21.8) | 42.7 (38.1; 47.6) |
P30 (95% CI) | 29.4 (26.8; 32.0) | 88.6 (86.7; 90.4) | 16.8 (14.1; 19.0) | 89.3 (87.1; 91.5) | 51.4 (46.7; 56.1) | 87.2 (84.0; 90.3) |
<60 ml/min/1.73 m 2 | ||||||
IQR (95% CI) | 1.04 (0.90; 1.14) | 0.31 (0.29; 0.45) | 0.79 (0.65; 0.99) | 0.26 (0.22; 0.37) | 0.67 (0.46; 0.93) | 0.37 (0.24; 0.61) |
P10 (95% CI) | 0.8 (0.0; 2.5) | 33.6 (25.1; 42.1) | 0.0 (0.0; 0.0) | 31.1 (19.1; 42.0) | 1.6 (0.0; 5.0) | 36.1 (24.0; 48.1) |
P30 (95% CI) | 10.9 (5.3; 16.5) | 67.5 (58.7; 75.6) | 0.0 (0.0; 0.0) | 62.1 (49.5; 74.6) | 21.3 (11.0; 35.5) | 72.1 (61.0; 83.9) |
60–89 ml/min/1.73 m 2 | ||||||
IQR (95% CI) | 0.42 (0.36; 0.46) | 0.23 (0.20; 0.26) | 0.35 (0.30; 0.40) | 0.21 (0.18; 0.24) | 0.41 (0.30; 0.51) | 0.21 (0.17; 0.32) |
P10 (95% CI) | 3.0 (1.0; 5.1) | 49.5 (45.5; 52.5) | 0.0 (0.0; 0.0) | 46.4 (38.8; 54.4) | 7.1 (4.0; 10.2) | 45.1 (36.6; 54.3) |
P30 (95% CI) | 10.3 (6.8; 13.9) | 89.0 (85.5; 92.7) | 0.0 (0.0; 0.0) | 90.4 (85.3; 94.8) | 23.9 (18.7; 29.1) | 87.6 (81.5; 93.7) |
≥90 ml/min/1.73 m 2 | ||||||
IQR (95% CI) | 0.32 (0.31; 0.34) | 0.21 (0.19; 0.23) | 0.28 (0.26; 0.31) | 0.18 (0.17; 0.21) | 0.24 (0.21; 0.27) | 0.20 (0.17; 0.24) |
P10 (95% CI) | 11.2 (9.0; 13.5) | 49.5 (45.5; 52.5) | 3.8 (2.2; 5.5) | 51.7 (47.5; 56.0) | 27.0 (21.5; 32.4) | 43.4 (37.3; 49.4) |
P30 (95% CI) | 38.5 (35.5; 41.8) | 91.2 (89.6; 93.5) | 23.3 (19.7; 26.8) | 92.0 (89.8; 94.3) | 70.7 (65.1; 72.3) | 90.6 (87.0; 94.2) |
IQR: IQR of the ratio of eGFR to mGFR; P10 and P30: within 10% and 30% limits above and below the mGFR.